Linda Park

Most of Linda's work has been genre films or tv! (Not that I'm complaining...)
Regular cast member on four series, three of which were genre.
And, in my opinion, she's one of the few reasons to watch the first three seasons of Enterprise! (The fourth, and final, season was actually pretty good!)
Linda's a tae kwan do black belt and gifted ballroom dancer, as well as the founder of the Underground Asylum theater company.

Genre appearances include...
House MD "The Fix"
Mentalist "BloodHounds"
Crash (Maggie Cheon)
Infestation(Leechee)
Women's Murder Club (Denise Kwon)
Honor(Kate)
Raines (Sally Lance)
Spectres aka Soul Survivor (Renee Hansen)
Enterprise / Star Trek: Enterprise
(Hoshi Sato/Empress Sato the First)
Taken (Party Goer)
Jurassic Park III(Hannah)
Check out...
Linda's Official WebSite
The Linda Park FanSite

Alicia Silverstone (Jarecki)

Hey, another Alicia!
A modern "flower child" type, Alicia first made a splash as a psychotic ingenue in films The Crush and The BabySitter and as a ditsy ingenue in the film Clueless.
Very involved in ecological and political causes, Alicia recently did a (tastefully) nude ad for PETA (which I've linked below).

Genre appearances include...
Vamps (Goody)
Tropic Thunder (Herself)
Silence Becomes You (Violet)
Alex Rider: Operation StormBreaker (Jack Starbright)
Scooby Doo 2: Monsters Unleashed / Scooby Doo 2: Monsters Unleashed [VG] (Heather)
Scorched (Sheila Rilo)
Rock My Worldaka Global Heresy (Natalie Bevin)
True Crime (Mary Giordano)
Hideaway (Regina)
Blast from the Past (Eve)
Batman and Robin (Batgirl / Barbara Wilson)

Check out...
The Kind Life
(Alicia's personal site about the vegan lifestyle)
Alicia at PETA
Alicia / Batgirl Tribute Page

Other actresses to play Batgirl include...
No one else has played Batgirl / Barbara Wilson (niece of Bruce Wayne's butler, Alfred Pennyworth).
All the other Batgirls have been Barbara Gordon (daughter / niece of Commissioner James Gordon)
(You thought I was gonna list over a dozen other Batgirls?)

Alicia Keys

Yet another singer (albeit a Grammy-Award winning performer) turned actress, Alicia made a cameo in an episode of Charmed, then hit the screen shooting as a lesbian assassin in Smokin' Aces.and received kudos for her dramatic ability in Secret Life of Bees!
UPDATE: Props to Ms. Keys for yet another Grammy win! Way to go, lady!

Genre appearances include...
Quantum of Solace[22nd Eon James Bond]
(co-performer w/ Jack White: main theme "Another Way To Die")
Hollywood Homicide(performer: "A Woman's Worth")
Dr. Dolittle 2(performer: "Rear View Mirror")
The Backyardiagans"Mission to Mars" (Boinga's Mom / performer: "Almost Everything is Boinga")
Smokin' Aces(Georgia Sykes)
Charmed"Size Matters"

Check out:

Alicia's Official Site
Alicia Keys Online (the #1 Source for ALL Things Alicia, according to them)

Elise Neal

Equally-adept at drama or comedy, Elise's first ongoing prime-time series role (after a stint on the soap Loving and numerous tv guest-apperances) was on SeaQuest DSV's revamp into SeaQuest 2032 as the ship's underwater fighter squadron commander.
She's best-known as Yvonne, wife and mother to The Hughleys on the sitcom of the same name.
(Trivia: she played a convincing teenager in the tv-movie Daddy's Girl when she was 30!)

Genre appearances include:
Jack and Janet Save the Planet (Christie)
K-Ville(Ayana Boulet)
CSI "Bodies in Motion"
A.U.S.A. "Pilot"
Mission to Mars(Debra Graham)
Fantasy Island [1998] "WishBoned"
Scream 2(Hallie McDaniel)
SeaQuest 2032(Lt. J.J. Fredricks)
PointMan "Take the Point"
Law & Order "Cradle to Grave"

Check out...
Her Official Site
Her appearance in King Magazine

Ming-Na Wen (Aanes/Zee)

Also known as "Ming-Na" or "Ming Wen", she has one of the more distinctive voices in the business, as shown by the extensive amount of animation voice-over work she's done in both tv and film!
Ming's demonstrated her acting chops in The Joy Luck Club and ER and her action prowess in the first Street Fighter film and Push (which is, ironically, opening shortly before the new Street Fighter film debuts).
Note: I complained about her lack of fighting ability in Street Fighter, but she has improved, as shown by her performanaces in Vanished and Push!
UPDATE: Ming's been cast as Agent Melinda May in Joss Whedon's S.H.I.E.L.D. TV pilot!

Genre credits include...
Agents of S.H.I.E.L.D. (Agent Melinda May)
StarGate Universe aka SGU (Camille Wray)

Push (Emily Hu)
Prom Night[2008] (Dr. Elisha Crowe)
Vanished (Agent Lin Mei)
Kingdom Hearts II[VG] / Mulan II/ Mulan/ House of Mouse (Fa Mulan)
The Batman (Detective Ellen Yin)
Spawn 3: Ultimate Battle/ Todd McFarlane's Spawn(Jade / Lisa Wu)
Final Fantasy: the Spirits Within/ Aki's Dream (Dr. Aki Ross)
Street Fighter/ Street Fighter the Movie[VG] (Chun-Li Zang)
Vanishing Son II / Vanishing Son IV (Mai)
StarQuest aka Terminal Voyage aka Star Voyager (Han)

Check out..
Ming-Na's Official Site
Ming-Na on Twitter

Other actress to play Fa Mulan:
Lea Salonga performed all of Mulan's singing to Ming's voice acting in the various Mulan films.
Other actresses to play Chun-Li include:
Kristen Kreuk in Street Fighter: the Legend of Chun-Li
Chingmy Yau in Future Cops
(and, no, I'm not going to list all the actresses who did voice work for Chun-Li's anime and video game appearances. You can Google them...)